Lebaka la tumor necrosis le bitsoa protheine e ngata ea extracellular, e hlahisoang ke lisele tsa immunocompetent (macrophages, eosinophils). Ka ho etsa lisele tse ling tsa 'mele, protheine ena e baka liphello tse latelang:
- ho potlaka ha metabolism;
- fetola ka ho khoneha ha marako a methapo ea mali;
- tlhahiso e eketsehileng ea li-interleukin (1, 6, 8);
- ho sireletsoa likokoana-hloko tsa intraellular;
- molao oa tsamaiso ea likokoana-hloko;
- tšusumetso e mpe.
Tlhahlobo ea mali bakeng sa ntlha ea tumor necrosis
Kaha ntlha ea tumor necrosis e nka karolo e 'ngoe le e' ngoe e etsoang ke 'mele ea' mele, ho tsepamisa mohopolo maling ho khetholloa ke matla a ho ruruha. Haeba tlhahlobo ea mali e bontša hore ntlha ea tumor necrosis e phahame, joale sena se ka bontša mafu a joalo:
- maloetse a tšoaetsanoang a matla (lefu la sebete la C, tšoaetso ea herpes, endocarditis, joalo-joalo);
- sepsis ;
- boemo bo tšosang haholo;
- lefu la pelo la kelello;
- psoriasis;
- mafu a seoa;
- ho hana ha litho tsa 'mele tse fetisitsoeng;
- ho ruruha ha methapo ea mafu ea pelo le boko;
- boloetse bo sa foleng ba bronchopulmonary;
- maloetse a boipheliso ;
- likokoana-hloko, joalo-joalo.
Sefuba sa necrosis sesosa sa oncology
Ho tseba hore na bothata ba kankere ea necrosis bo bohlokoa hakae ha ho hlahlojoa tsela ea kankere. Mabapi le lisele tsa tumor, protheine ena e bontša mosebetsi, o hlalositsoeng ka hemorrhagic necrosis ea lisele tse kotsi tse sa tsoeleng pele ntle le ho senya lisele tse phetseng hantle. E itšetlehile ka ntlha ea tumor necrosis e arohaneng ka tsela e ikhethang ho tsoa ho mali a bafani, lithethefatsi tse nang le lisebelisuoa tse matlafatsang li hlahisoa, ha li e-na le phello e fokolang ea 'mele' meleng. Ka mohlala, ka thuso ea meriana ea Refnot phekolo ea kankere ea matsoele e etsoa.