Digoxin ke lithethefatsi tse sebelisoang haholo ho phekola mafu a pelo, hangata ka mokhoa oa matlapa. O bitsoa sehlopha sa meriana ea pelo ea glycosides - meriana ea litlama, e nang le cardiotonic le antiarrhythm effect.
Mokhoa oa lik'hemik'hale le oa phekolo ea matlapa a Digoxin
Motsoako o sebetsang oa lithethefatsi Digoxidine ke ntho e le 'ngoe digoxidine, e arohaneng le makhasi a semela, digitalis boolly. Likarolo tse ling tsa foromo ea thepa ea lithethefatsi ke:
- silicon dioxide colloidal;
- gelatin;
- stearate ea magnesium;
- talc;
- starch ho tloha poone;
- lactose monohydrate.
Ha e nkoa ka molomo, sethethefatsi se kenngoa hantle ka pampiri ea meno 'me se lemoha phello ea sona hoo e batlang e le lihora tse 2-3 kamora ho tsuba. Tlhahlobo ea phekolo e nka bonyane lihora tse 6. Pheko e kentse haholo ka motsoako.
Tlas'a tšusumetso ea ntho e sebetsang ea lithethefatsi, liphello tse latelang li hlokomeloa:
- ho eketseha ka matla a mericardial mescle contractions (phello e ntle ea inotropic);
- keketseho ea boholo ba mali;
- fokotseha ka makhetlo a mangata a ho thibela ha mesifa ea pelo;
- ho fokotseha ha molumo oa li-systolic le o fokolang oa diastolic oa pelo;
- ho fokotseha ha tlhahlobo ea oksijene ea mochine oa lik'hemik'hale;
- ketso e khahlanong le matla (ka ho fokotsa lebelo la menahano ka mokhoa oa atrioventricular le ho eketsa nako e sebetsang ea refractivity);
- vasodilator effect (ka ho ferekanngoa ka morao ho pelo ea ho hlōleha );
- phello e bonolo ea diuretic;
- fokotsa phefumoloho e khutšoanyane;
- fokotseha ka edema, joalo-joalo.
Lipontšo tsa tšebeliso ea lithethefatsi Digoxin
Lintlha tse ka sehloohong tsa tšebeliso ea meriana Digoxin ke li-diagnostics tse joalo:
- ho sa feleng ha pelo ea ho hloleha ha lihlopha tsa II, III le IV tse sebetsang (e le karolo ea phekolo e rarahaneng ea lithethefatsi);
- mofuta o fokolang oa mafura a atrial;
- ho fokotsa ho fokotsa lefu la 'mele;
- paroxysmal supraventricular tachycardia.
Ho latela litekanyetso ka tšebeliso ea matlapa a Digoxin
Ha e le lithethefatsi tsohle tsa sehlopha sa pelo ea glycosides, tekanyo ea Digoxin e khethoa ka hloko ke ngaka e kileng ea e-ba teng, e nahanne ka litšobotsi tsa motho ka mong oa 'mele oa hae, boima le mofuta oa litsela tsa pathological, le methapo ea pelo ea electrocardiogram.
Ka mohlala, e 'ngoe ea mekhoa ea ho noa moriana ka foromo ea lipolisi e akarelletsa ho behoa ha Digoxin ka palo ea 0,25 mg ka makhetlo a 4-5 letsatsing la pele la phekolo,' me matsatsing a latelang - 0.25 mg ka makhetlo a mararo ho isa ho a le mong ka letsatsi. Tabeng ena, kamohelo e lokela ho etsoa tlasa tlhokomelo ea lingaka.
Ka mor'a hore phekolo e hlokahale (hangata ka mor'a matsatsi a 7 ho isa ho a 10), tekanyo ea litekanyetso e fokotsehile, tekanyo ea tlhokomelo ea lithethefatsi e laeloa bakeng sa tšebeliso ea nako e telele. Ho khethoa ha liente tse entravenous, e le molao, ho hlokahala feela ha ho e-ba thata ho potoloha ha lipalesa.
Litla-morao tsa Digoxin:
- ho nyekeloa ke pelo;
- ho hlatsa;
- mathata a likoti;
- ho hloka takatso ea lijo;
- hlooho;
- botsoa;
- mathata a ho robala;
- ho hloleha ha pelo;
- ho tsoa mali ho eketsehileng;
- ho hlohlona;
- urticaria;
- bofokoli bo boholo;
- mokhathala, joalo-joalo.
Litlhaloso tse amanang le tšebeliso ea Digoxin:
- ho tahoa ke li-glycosides tsa pelo;
- tšoaetso e matla ea lik'hemik'hale;
- Angina e tsitsitseng ;
- Lefu la Wolff-Parkinson-White;
- atrioventricular block;
- bradycardia e nang le lipontšo tse kholo tsa bongaka;
- lefu le leholo la lefu la pelo;
- mitral stenosis le tse ling.