Lithethefatsi tse sa thibeleng ho ruruha (NSAIDs) ke sehlopha sa meriana e atlehang e nang le li-antipyretic, li-anti-inflammatory le li-analgesic.
Ka hona, lithethefatsi tsena li thusa ho fokotsa bohloko, feberu le ho ruruha. Ketso ea bona e itšetlehile ka thibelo ea li-enzyme tse itseng, tseo ho tsona ho qalang lintho tse etsang hore ho ruruha ho etsoe 'meleng. Ho fapana le glucocorticoids (li-hormone agents), phello ea eona e tšoanang, meriana e se nang steroid ea meriana ha e na matšoele a joalo a sa rateheng.
Ho phaella moo, li-NSAID tse ling li na le phello e khahlanong le aggregation (dilution, ntlafatso ea mali fluidity), hammoho le phello ea immunosuppressive (khatello ea maiketsetso ea ho itšireletsa mafung).
Lipontšo tsa tšebeliso ea li-NSAID
Ka kakaretso, lithethefatsi tse se nang steroidal tse khahlanong le ho ruruha li sebelisoa mafu a maholo le a sa foleng, a tsamaeang le ho ruruha le bohloko. A re thathamiseng maloetse a 'maloa, ao litokisetso tse latelang tsa sehlopha se fanoeng li khothalletsoang:
- osteoarthritis;
- ramatiki ea ramatiki;
- gout;
- hlooho, migraine ;
- feberu;
- mafu a kelello;
- dysmenorrhea;
- colic ea renal;
- metastase ea masapo;
- lefu la lefu la postoperative;
- ho ruruha ha masapo.
Lethathamo la lithethefatsi tse se nang steroidal tse khahlanong le ho ruruha
Lethathamo la lithethefatsi tsa morao-rao tse seng khahlanong le ho ruruha hona joale li le bophara haholo. Li aroloa ho ea ka lik'hemik'hale le sebōpeho sa mosebetsi ona. Mefuta e meng e sa tšoaneng ea lithethefatsi tse sa thibelang ho ruruha li arotsoe: lipilisi, li-capsules, mafura, li-gel, suppositories, tharollo e ka kenngoa meriana, joalo-joalo.
Nahana ka mefuta e meholo ea li-NSAID:
- Salicylates:
- Aspirin;
- Diflunisal;
- lysine monoacetyl salicylate.
- Indomethacin;
- Sulindak;
- Ena ke eelander.
- Diclofenac ;
- Aceclofenac.
- Ibuprofen;
- Ketoprofen;
- Tiaprofenic acid;
- Naproxen;
- Flurbiprofen;
- Fenbufen;
- Fenoprofen;
- Nabumethon.
- Lornoxicam;
- Tenoxicam;
- Piroxicam;
- Meloksikam.
- Rofecoxib;
- Nimesulide;
- Celecoxib.
Ho tsoa litokisetsong tse fanoeng mabapi le ketso ea analgesic, lithethefatsi tse kang Ketorolac, Ketoprofen, Diclofenac, Indomethacin li atleha haholo. Lintho tse ntle ka ho fetisisa tse khahlanong le ho ruruha ke Indomethacin, Flurbiprofen, Diclofenac le Piroxicam.
Ke habohlokoa ho hlokomela hore lithethefatsi tse se nang steroidal tse khahlanong le ho ruruha li rekisoa tlas'a mabitso a sa tšoaneng a khoebo. Ka hona, ha u reka meriana pharmacy, pele ho tsohle, motho o lokela ho ela hloko lebitso la machaba.
Lithethefatsi tse sa khahlanong le ho ruruha tsa moloko o mocha
Lithethefatsi tse khahlanong le ho ruruha ha moloko o mocha li sebetsa ka mokhoa o khethehileng 'me li bontša mosebetsi o phahameng ka ho fetisisa ho bapisoa le ba pelehi ba bona. Tabeng ena, ha ho na litla-morao tse tsoang ho pampiri ea meno.
Baemeli ba lithethefatsi tse ncha tsa sehlopha sa NSAID ke oxycam.
NSAID li boetse li na le li-contraindications tsa tsona:
- likokoana-hloko tse matlafetseng le tse bolaeang lefu la tšoaetso ea masapo;
- ho hatakeloa ha sebete le liphio;
- cytopenia;
- ho ima;
- ho hloka kutloano ka bomong.