Mefuta e phahameng ea triglycerides le k'holeseterole maling e nkoa e le boemo bo kotsi bo ka bakang nts'etso-pele ea maloetse a pelo. Ho fokotsa mahlaseli a lik'hemik'hale tsena ho fanoa ka lithethefatsi tse khethehileng, tse nkiloeng nako e telele Ke habohlokoa hore mokuli a lekanyetse liqabang tsohle pele a noa li-statins-pro le contra, a ele hloko litla-morao tsa meriana ena le mathata a ka 'nang a hlaha a phekolo.
Melemo le kotsi ea li-statin bakeng sa 'mele
Ho hlahisa k'holeseterole ho na le mekhahlelo e 'maloa ea pele le nts'etsopele ea enzyme e bitsoang mevalonate. Li-Statins li kena-kenana le sebopeho sa eona qalong, 'me ka hona, li thibela tlhahiso ea triglycerides le k'holeseterole.
Nakong ea lipatlisiso tsa bongaka le liteko, ho fumanoe hore lithethefatsi tseo ho buisanoang le tsona li na le liphello tse latelang:
- Ho fokotsa bongata ba k'holeseterole maling a mali (e leng - ka 35-45%, e kotsi - ka 45-60%).
- Ho fokotsa kotsi ea mafu a pelo ea methapo ea pelo, ho thibela likokoana-hloko tsa pelo, lefu la atherosclerosis, lipolao, litlhaselo tsa sischemic.
- Ho felisoa ha sebete sa k'holeseterole sebeteng.
- Eketsa khohlano ea apoliprotein A le k'holeseterole ea bohlokoa.
Hape, tšebeliso ea li-statins ke ho ntlafatsa bophelo bo botle ba bakuli esita le ka boteng ba lefu la pelo ka ho matlafatsa le ho hloekisa marako a methapo ea mali. Ka nako e ts'oanang, meriana ena ha e na metagenic le carcinogen effect.
Ho sa tsotellehe karolo e hlakileng e ntle ea meriana e hlalositsoeng, litsebi tsa morao tjena li na le litaelo tse nyenyane le tse nyenyane. Sena se bakoa ke litla-morao tse ling tsa ho nka li-statins:
- Fokotsa boemong ba se kotsi feela, empa hape le k'holeseterole eohle, e leng e hlokahalang bakeng sa ho sebetsa ka tsela e tloaelehileng ea 'mele, ho boloka elasticity ea methapo ea mali.
- Liphello tse mpe sebeteng parenchyma ho sitisa tlhahiso ea lik'hemik'hale tse etellang k'holeseterole.
- Ho hlaphoheloa ka potlako ea mohopolo oa pele oa k'holeseterole e phahameng nakong ea phekolo ea phekolo, e etsang hore pilisi e nke hoo e batlang e le bophelo bohle.
Ntle le mathata ana, ho na le mefokolo e meng e mengata e tebileng ea lithethefatsi tse joalo.
Litla-morao tse kotsi tsa li-statin
Ketsahalo e tloaelehileng ka ho fetisisa ke:
- asthenic syndrome;
- ho nyekeloa ke pelo;
- ho hlobaela;
- ho patoa;
- hlooho;
- ho itšepa;
- letšollo;
- myalgia;
- mahlaba a mpa;
- migraine;
- khatello e tloaelehileng, bofokoli;
- paresthesia le hypoesthesia;
- botsoa;
- phekolo ea meriana;
- liketsahalo tsa amnesia;
- ho fokola;
- lejoe le hloekileng la jaundice;
- ho hlatsa;
- hepatitis;
- anorexia;
- ho tepella;
- li-spasms ka mesifa;
- myositis;
- ramatiki ea manonyeletso a maholo;
- myopathy;
- bohloko boemong ba mokokotlo oa mokokotlo;
- erythema e feteletseng;
- ho phatloha letlalong;
- anaphylaxis;
- urticaria le ho hlohlona;
- Lefu la Lyell ;
- lefu la tsoekere;
- thrombocytopenia;
- hypoglycemia;
- botenya;
- edema ea pherekano.
E 'ngoe ea litla-morao tse kotsi tsa li-statins, ho na le mathata a bokooa a sa khaotseng. Liteko tse ngata li bontšitse hore makhetlong a mangata a phekolo ea lithethefatsi ho nahanoa, ho fokola ha mohopolo, mesebetsi ea puo,
Ka hona, ho nka li-statins ho hlokahala feela maemong a feteletseng:
- Matšoao a "Ischemic" a nang le kotsi e eketsehileng ea lefu la seoa kapa lefu la pelo.
- Phekolo ea lefu le bohloko la lefu la pelo.
- Ts'ebetso ea ho tsosolosa lijaneng kapa pelo.